NMR Spectroscopist/Specialist (CDMO/Pharma) Job at Porton Pharma Solutions Ltd., Cranbury, NJ

d2xWZDJEQ3ZLbmxtZUZLaWxBaEx5M2FPL0E9PQ==
  • Porton Pharma Solutions Ltd.
  • Cranbury, NJ

Job Description

Job Title: NMR Spectroscopist

Job Type: Full-time

Work Location: On-site Cranbury, NJ (with the possibility of assignment to South Plainfield, NJ).

Job Description:

We are seeking an experienced NMR Spectroscopist to join our team in the CDMO industry. The ideal candidate will be responsible for the maintenance and buildout of our NMR facility, troubleshooting NMR instrumentation, and performing structural elucidation of small molecule drug substances. This role also involves identifying and elucidating impurities and degradants, and effectively communicating NMR data for structural analysis. Strong teamwork and excellent communication skills are essential.

J-STAR Research, Inc. is a subsidiary of Porton that specializes in providing contract chemistry services to the biopharmaceutical and biotechnology industry. Our primary focus is resolving intricate chemistry problems relating to Active Pharmaceutical Ingredients and Intermediates in the preclinical and clinical development phases. We are adept in synthetic chemistry and process research services, which include Process Chemistry, Quality Control, Good Manufacturing Practice, Quality Assurance, Crystallization Research and Development, Solid Form and Polymorph Screening, Catalysis Screening and Enabling Technology, High Potent Compound Handling (HPAPI), Impurity Isolation and Structural Elucidation, and Preformulation and Formulation Research and Development.

At J-Star, there are 5 NMR systems including one 500 MHz H/C/N Cryoprobe as well as two 400 MHz Bruker systems with multiple-nuclear and variable temperature capabilities. We are hiring an NMR Spectroscopist to support project team decisions and improve the speedy delivery of API for our clients.

Responsibilities:

  • Oversee the general maintenance and development of the NMR facility.
  • Independently troubleshoot and resolve issues with NMR instrumentation.
  • Perform structural elucidation of small molecule drug substances, intermediates, and starting materials.
  • Identify and elucidate the structures of related impurities and degradants from API synthesis, fate and purge, and stress degradation studies.
  • Provide clear oral and written explanations of NMR data for structural elucidation.
  • Collaborate effectively with a team of chemists.

Requirements:

  • BS, MS, Ph.D. with 5+ years or MS with 10+ years of post-graduate industrial or academic experience in small molecule NMR data collection and interpretation.
  • Degree in Organic Chemistry, Physical Chemistry, Pharmaceutical Sciences, Physics, or a related field.
  • Experience troubleshooting NMR hardware and software (Bruker and Varian), including magnets, consoles, conventional and cryoprobes, autosamplers, and workstations (Windows and Linux).
  • Demonstrated ability to creatively apply NMR techniques to pharmaceutical problems.
  • Strong understanding and application of NMR theory for solving chemical structures and interactions of small molecules.
  • Experience using 1D (1H, 13C, 19F, 15N, etc.) and 2D (COSY, ROESY, HSQC, HMBC, TOCSY, etc.) multinuclear solution-state NMR techniques on high-field NMR instruments (300-500 MHz) equipped with conventional and cryoprobe technology.

Experience:

  • NMR Experience: 4 years (Required)
  • Pharmaceutical CDMO Industry Experience: 5 years (Preferred)

Relocation:

  • Must be able to relocate to Cranbury and South Plainfield, NJ before starting work (Required)

Work Location:

  • In-person

Job Tags

Full time, Contract work, Relocation,

Similar Jobs

Compunnel Inc.

Toxicology Associate Scientist Job at Compunnel Inc.

 ...2-5 yrs experience: Laboratory w/ rodent animal handling, basic science skills; BS Degree required Any exposure to common allergens?...  ...weights, clinical observations, holding for eye exams, and other in-life study functions. Collecting biological samples which can... 

CBS Therapy

School Social Worker Job at CBS Therapy

 ...About Us CBS Therapy is the premier provider of School-Based and Pediatric Special Education staffing. We are owned and directed by two Speech Language Pathologists who are passionate about delivering highly qualified therapists and staff to our clients and community.... 

Creative Circle

Art Director Job at Creative Circle

 ...Art Director - Full-Time & On-site To be considered, we must see agency experience (hospitality is great too!!) in your resume and portfolio. Location: Dania, FL On-Site requirement: 5 days per week - no flex here Rate / Salary Range: $90-$95K + benefits... 

Belmont Park Village

Host Job at Belmont Park Village

 ...all related departments to ensure smooth service. Responding to guest requests for special arrangements (e.g. transportation, restaurant reservations, etc.). Anticipating operational needs and providing the respective support; identifying any key areas of concern... 

French Corner Soho

Weekend Retail Sales Associate Job at French Corner Soho

 ...customer service and ensuring a unique shopping experience for all our customers. Role Description This is a part-time on-site role for a Weekend Sales Associate (Friday, Saturday, and Sunday). Associate would be on schedule for full day shifts (10AM-7PM). The...